Vitamin B5 (D-Calcium Pantothenate)

    • Product Name: Vitamin B5 (D-Calcium Pantothenate)
    • Chemical Name (IUPAC): Calcium (R)-2,4-dihydroxy-3,3-dimethylbutyramido)propanoate
    • CAS No.: 137-08-6
    • Chemical Formula: C18H32CaN2O10
    • Form/Physical State: Powder
    • Factroy Site: No. 777, Shengli West Road, Yuhui District, Bengbu City, Anhui Province, China
    • Price Inquiry: sales7@bouling-chem.com
    • Manufacturer: Anhui BBCA Group Co., Ltd
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    Specifications

    HS Code

    141702

    Chemical Name D-Calcium Pantothenate
    Common Name Vitamin B5
    Molecular Formula C18H32CaN2O10
    Molar Mass 476.53 g/mol
    Appearance White, crystalline powder
    Solubility In Water Freely soluble
    Melting Point 190°C (decomposes)
    Cas Number 137-08-6
    Storage Conditions Store in a cool, dry place
    Function Essential nutrient for energy metabolism
    Stability Stable under normal conditions
    Odor Odorless
    Bioavailability High when taken orally
    Usage Dietary supplement, food fortification
    Synonyms Calcium pantothenate, Pantothenic acid calcium salt

    As an accredited Vitamin B5 (D-Calcium Pantothenate) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Application of Vitamin B5 (D-Calcium Pantothenate)

    Purity 99%: Vitamin B5 (D-Calcium Pantothenate) with purity 99% is used in dietary supplements manufacturing, where it ensures high bioavailability and rapid absorption.

    Particle Size 60 mesh: Vitamin B5 (D-Calcium Pantothenate) with particle size 60 mesh is used in tablet formulation, where it enables uniform blending and consistent tablet hardness.

    Stability Temperature 40°C: Vitamin B5 (D-Calcium Pantothenate) with stability at 40°C is used in beverage fortification, where it maintains vitamin potency during storage.

    Moisture Content ≤ 5%: Vitamin B5 (D-Calcium Pantothenate) with moisture content ≤ 5% is used in premixed nutritional powders, where it improves shelf life and reduces caking.

    Assay 98-101%: Vitamin B5 (D-Calcium Pantothenate) with assay 98-101% is used in infant formula production, where it guarantees precise nutritional labeling and compliance with safety standards.

    Bulk Density 0.5 g/cm³: Vitamin B5 (D-Calcium Pantothenate) with bulk density 0.5 g/cm³ is used in encapsulation processes, where it allows efficient capsule filling and dose accuracy.

    Melting Point 190°C: Vitamin B5 (D-Calcium Pantothenate) with a melting point of 190°C is used in pharmaceutical granulation, where it provides thermal stability during processing.

    Solubility in Water 50 g/L: Vitamin B5 (D-Calcium Pantothenate) with solubility in water 50 g/L is used in liquid vitamin formulations, where it ensures complete solubilization and homogeneous distribution.

    Packing & Storage
    Packing White, tamper-evident HDPE bottle containing 500g of Vitamin B5 (D-Calcium Pantothenate) powder, labeled with usage and safety instructions.
    Container Loading (20′ FCL) 20′ FCL contains approximately 12 MT of D-Calcium Pantothenate, packed in 25kg drums or cartons, securely loaded for export.
    Shipping Vitamin B5 (D-Calcium Pantothenate) is shipped in tightly sealed containers, protected from moisture and direct sunlight. Standard packaging includes fiber drums or HDPE bags with inner liners, meeting safety and quality regulations. Shipping is conducted under ambient temperature, with labeling compliant with international transport and handling standards for food-grade chemicals.
    Storage Vitamin B5 (D-Calcium Pantothenate) should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from moisture, heat, and direct sunlight. Keep the container protected from incompatible substances and sources of ignition. Ensure storage conditions prevent contamination and degradation, and always keep it out of reach of children and unauthorized personnel.
    Shelf Life Vitamin B5 (D-Calcium Pantothenate) typically has a shelf life of 24-36 months when stored in cool, dry conditions.
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    More Introduction

    Vitamin B5 (D-Calcium Pantothenate): A Vital Ingredient from the Manufacturer’s Perspective

    Introduction to Vitamin B5 (D-Calcium Pantothenate)

    Years of producing vitamins at the source have taught us that not every batch is the same, not every process delivers what formulations promise on paper. Among the portfolio, D-Calcium Pantothenate stands out for its flexibility and reliability. Back at the plant, the complexity of producing this form of Vitamin B5 isn't lost on anyone involved. We work with real substances, responding to the quirks of every raw material lot, always aiming to deliver a product that clears both our internal benchmarks and global food or pharma-grade standards.

    D-Calcium Pantothenate, the calcium salt of the water-soluble vitamin B5, makes its way into a surprising range of applications. Our own batches often end up in nutritional supplements, food fortification premixes, and feed blends. It’s also a regular for some local and overseas pharmaceutical clients. Our facility typically produces the USP/EP grade, with most output tailored to specifications of the international market, since that’s where demand sits. The compound appears as a white, odorless powder—easy to handle and stable under a variety of processing conditions.

    Manufacturing Perspective: Quality, Consistency, and Responsiveness

    From synthesis to purification and drying, every step asks for close attention. Every operator here knows how sensitive D-Calcium Pantothenate is to heat, moisture, and contaminants during final drying and packaging. A few seconds of lax vigilance might threaten an entire day’s work, sacrificing the free-flowing texture or producing fine dust that's hard to manage downstream.

    Lab checks are regular. Meeting USP or EP specifications is about hitting targets for calcium content, moisture levels, specific rotation, and heavy metals. Where some manufacturers might get comfortable with minimum required thresholds, we’ve learned over years of feedback from feed and nutrition plants that the "invisible" details mean fewer production headaches later. For example, too much dust and some blending systems jam; too much moisture and shelf life shortens. False assumptions are costly—our own customers told us this straight.

    Our production lines feature continuous filtration and multi-step washing, because starting clean cuts down on downstream troubleshooting. Older batch processes used to cause more headaches in-house due to variations in crystal size. With newer processes, we spend less time reworking off-spec lots, which gets product out the door faster for everyone. Operational experience keeps teaching us to double-check every variable, even where regulations don’t force our hand.

    Vitamin B5 and Its Broad Impact

    It’s easy to forget that behind every supplement bottle lining a supermarket shelf lies a mountain of regulated input from producers. We’ve seen firsthand where our D-Calcium Pantothenate ends up: chewable multivitamins in South America, tablet blends for energy drinks in the Middle East, animal feed premixes for dairy farms in Northern Europe. In every setting, B5 plays its part supporting metabolic pathways, optimizing protein and fat utilization, and keeping production animals healthy.

    Users rarely see the difference between B-vitamin forms, but as a supplier we know the small details influence outcomes. For liquid supplements, solubility matters. For compressed tablets, flowability and stability are priorities. Our largest single order last year involved a food fortification project overseas: their technical constraints forced us to manage particle size down to a narrow band, since the product needed to be dispersed uniformly in ready-to-eat cereals. Because we oversee the full process in-house, we're able to adjust crystallization to meet demanding particle profiles. The customer’s rate of reject batches dropped, and for us that translated into fewer returned consignments and a tighter business relationship.

    Comparing D-Calcium Pantothenate to Other B5 Sources

    Many of our customers ask about alternatives like Pantothenic Acid—the raw, non-salt form of B5. Pantothenic acid itself is sensitive to heat, light, and acidity, making it a complicated ingredient in the real world. For multivitamin products or fortifying juices, its instability shrinks usable shelf life. D-Calcium Pantothenate essentially solves the problem. The calcium salt form tolerates standard tablet and food processing, faces less degradation under normal manufacturing, and blends consistently both with synthetic and natural blends. This means less loss during long storage and distribution. Our experience working with both forms, from high-speed lines in industrial tablet production to small batch manual blending, pulled us early toward D-Calcium Pantothenate as the best fit for nearly all uses.

    Another option some customers have explored uses D-Pantothenol—an alcohol derivative that converts into B5 in the body. We produced trial batches a few years ago, but quickly found that, in the context of large-scale food fortification, Pantothenol didn’t meet shelf life predictions under hot, humid transport. Feed producers, too, reported inconsistent results.

    D-Calcium Pantothenate bypasses many of these issues. Over the years, we’ve fielded direct technical questions from our partners, many wanting to know why one batch seems to perform better than another. The differences almost always trace back to crystal size or minor moisture fluctuations—manufacturing details that don’t show up on broad consumer labels. The right salt form brings consistency both for processing and biological uptake. You can see the impact not from a distance but through repeatable, trouble-free production cycles. Our sales always reflect repeat business from those who value reliability in ingredient sourcing, especially where final product testing is rigorous.

    Daily Experience: The Details That Define Quality

    Over time, our batch logs filled up with notes from operators about blending performance, yield rates, and feedback from downstream customers. For example, brands that manufacture effervescent tablets pointed out that granular D-Calcium Pantothenate gives more stable dissolution and less dust in high-speed lines. Our process shifted to accommodate this, refining drying and screening steps, reducing over-fines.

    Dust control is something we never stop talking about, both for worker safety and final application. A high dust product causes problems in plant environments, interrupts flow meters, and escapes packaging lines, raising both hygiene concerns and product waste. Our production method adds an extra step for particle sizing—not every supplier invests in this, but over the long haul the data supports it. It’s better for us and for everyone down the supply chain.

    Temperature stability stands out as well. Past experience with other forms of B5 revealed that some degrade even in moderate storage conditions, which becomes costly when dealing with international transit. D-Calcium Pantothenate weathered those tests—samples stored at elevated temperature for months still met potency targets. We log these results not just for compliance, but because the returns and rejections get expensive otherwise.

    Common Uses: Insights from Manufacturing Partners

    It's always instructive how customers deploy our product across industries. Nutritional supplement producers prize the compactness and flow properties of our crystalline D-Calcium Pantothenate for direct tablet compression. The consistent particle size and low moisture content let them run at scale without clumping or cross-contamination with hygroscopic actives.

    Food processors, especially those making cereal bars or powdered premixes, select our B5 because they need stability, both thermally and chemically. Heat and pressure during extrusion or baking can destroy lesser forms; D-Calcium Pantothenate holds up. Our direct communication with large-scale food brands turned up rare failures, usually tied back to unusual ingredients or processing errors, not from variation in our product.

    Feed manufacturers pay attention to homogeneity, since livestock feed must disperse evenly. Our product's physical properties address this requirement not just by design but through years of iterative feedback. On-site feed trials showed better vitamin recovery in finished mash compared to older pantothenate versions. Getting that “hands-on” feedback gives us something spec sheets never can.

    Regulatory Compliance and Traceability From the Source

    Years of audits and inspections by buyers and regulatory teams keep our standards aligned with market needs. We’ve handled everything from unexpected EU lab testing requests to intense U.S. FDA checks, and in every case, batch-level documentation from our own system kept us compliant. This means verified traceability for each kilogram that leaves our plant.

    Customers want trusted supply that protects their brands. We maintain detailed records not to fill binders but to catch deviations before they reach the customer. By managing quality in-house, we control cross-contamination risks, fake adulteration, and unapproved ingredient swaps. Our experienced staff recognize quality shifts early. Instances of off-color or odor from unusual raw material shipments once triggered batch quarantines, allowing us to prevent product recalls at the customer level. We view transparency as a necessity, not a marketing strategy.

    The Real-World Challenges of Sourcing and Scaling

    Market swings hit closer than most outside the supply chain realize. Supply chain snags—caused by anything from transport disruptions to sudden spikes in demand for fortified foods—test our ability to deliver. During global shortages of certain feedstock chemicals, we found that bulk buyers and resellers scrambled to lock in large orders, but our head-start in raw material stock management allowed steady delivery to standing accounts. Our direct production model kept us insulated against fluctuations that rippled through markets where intermediaries struggled to guarantee both purity and availability.

    Scaling production means re-calibrating everything from filtration pressure to drying cycle times. Our investment in large-scale reactors and automated monitoring came straight from customer-driven pressure for reliability. Years ago, limited infrastructure forced us to run smaller, inconsistent batches; result: unpredictable delivery timelines and uneven product quality. Now, production lines are set for long runs, minimizing batch-to-batch fluctuation and reducing lead times for large, time-sensitive projects.

    Environmental Responsibility and Waste Minimization

    Handling chemicals means grappling with the real impact of waste. Every lot that falls out of tolerance generates time, labor, and costs for responsible disposal—with B vitamins in particular, rejected batches mean more than lost profit; uncontrolled dumping can cause environmental burdens.

    We set up solvent recovery equipment years ago to handle byproducts safely and re-integrate streams where possible. In-vitro and in-process testing catch problems while they’re smaller. Some competitors accept higher batch rejection rates. Our approach is to re-work marginal product up to specification, slashing raw material wastage and fulfilling orders without creating excess environmental burden.

    Feedback from food and pharma buyers increasingly asks for detailed carbon footprint data. We gather the numbers so that customers further up the chain can clarify their own product claims—not just ticking a policy box but meeting the expectations of a marketplace that rewards sustainable practices.

    Supporting Customers Beyond Product Delivery

    Our role doesn’t stop at bulk shipment. Support teams field questions from customer process engineers, often troubleshooting blending or thermal stability issues in real time. Customers who run complex multivitamin tablet presses checked in last season, puzzled by compression problems. Our own staff visited their site, spotted particle segregation near the packaging hopper, and recommended remedial handling tips. Their rejection rate for the batch plummeted, strengthening supplier ties in ways specs alone never do.

    Supplements and food manufacturers often reach for generic B5 supplies without knowing how processing nuances affect their outputs. The most successful collaborations begin with direct communication: technical training for our partners, advice during formulation pilots, and routine sharing of test results. Years of manufacturing sharpened our conviction that technical support is what differentiates a direct manufacturer from distant resellers or traders.

    We back our own product, handling complaints and analyzing failed batches to root causes instead of defaulting to paperwork. Product returns turn into case studies for process refinement, feeding back into improved quality and reliability for everyone down the chain.

    Securing the Future: Meeting Demand for Clean-Label, High-Purity B5

    Trends in the food and supplement landscape continue to move toward higher demands for purity, traceability, and minimal additives. We balanced our internal R&D to support clean-label goals: minimizing process aids, sourcing certified raw materials, and maintaining allergen-free production lines. Our analytic lab expanded to address requirements for GMO status confirmation, allergen residue testing, and additional contaminant screenings adopted by some global brands.

    The journey from raw feedstock to finished D-Calcium Pantothenate is far from automatic. Decades at the production core highlighted what matters most: precise controls, direct response to real customer needs, technical follow-up, and a tight feedback loop for batch improvement. Partners at every stage—farmers, food processors, nutrition brands—entrust critical links in their chain to reliable B5. Our business keeps evolving around this reality.

    Building quality D-Calcium Pantothenate never happens by chance. The right mix of experience, tight controls, and direct relationships makes it possible to supply the consistent, on-spec ingredient our customers expect. We know this ingredient inside out—every step, every test, every feedback call. On the ground, this commitment shapes every lot that leaves our facility, no matter where it’s headed next.