L-Threonine

    • Product Name: L-Threonine
    • Chemical Name (IUPAC): (2S,3R)-2-Amino-3-hydroxybutanoic acid
    • CAS No.: 72-19-5
    • Chemical Formula: C4H9NO3
    • Form/Physical State: Crystalline powder
    • Factroy Site: No. 777, Shengli West Road, Yuhui District, Bengbu City, Anhui Province, China
    • Price Inquiry: sales3@ascent-chem.com
    • Manufacturer: Anhui BBCA Group Co., Ltd
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    Specifications

    HS Code

    819668

    Chemical Name L-Threonine
    Molecular Formula C4H9NO3
    Molar Mass 119.12 g/mol
    Appearance White crystalline powder
    Solubility In Water Very soluble
    Melting Point 256 °C (decomposes)
    Cas Number 72-19-5
    Isoelectric Point 5.6
    Purity Typically ≥ 98%
    Uses Nutritional supplement, feed additive
    Storage Conditions Store in cool, dry place
    Synonyms 2-Amino-3-hydroxybutyric acid

    As an accredited L-Threonine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Application of L-Threonine

    Purity 98%: L-Threonine with purity 98% is used in animal feed formulations, where it enhances protein synthesis and growth rates in livestock.

    Particle Size 100 Mesh: L-Threonine with particle size 100 mesh is used in premix manufacturing, where it provides uniform distribution and bioavailability in feed blends.

    USP Grade: L-Threonine USP grade is used in pharmaceutical production, where it ensures compliance with safety and efficacy standards for injectable solutions.

    Molecular Weight 119.12 g/mol: L-Threonine with molecular weight 119.12 g/mol is used in nutrient supplements, where it supports precise nutritional balance in dietary products.

    Stability up to 60°C: L-Threonine with stability up to 60°C is used in feed processing, where it maintains amino acid integrity during pelletization processes.

    Moisture Content <1%: L-Threonine with moisture content less than 1% is used in feed additives, where it prevents clumping and extends shelf life.

    Crystalline Form: L-Threonine in crystalline form is used in food enrichment, where it ensures rapid dissolution and homogenous mixing in beverage applications.

    Packing & Storage
    Packing L-Threonine is packaged in a 25kg white woven bag with blue labeling, featuring product details, safety symbols, and manufacturer information.
    Container Loading (20′ FCL) Container Loading (20′ FCL) for L-Threonine: 18-25 metric tons packed in 25kg bags on pallets, ensuring safe, efficient transport.
    Shipping L-Threonine is shipped in tightly sealed, moisture-resistant containers to prevent contamination and degradation. Packages are clearly labeled with hazard information, batch numbers, and handling instructions. During transport, containers are secured to avoid damage, stored in cool, dry conditions, and compliant with all applicable chemical shipping regulations and safety guidelines.
    Storage L-Threonine should be stored in a tightly sealed container in a cool, dry, and well-ventilated area away from incompatible substances. Keep it away from moisture and direct sunlight. Avoid exposure to excessive heat. Ensure the storage area is free from strong oxidizers and acids. Proper labeling and secure storage help prevent contamination and ensure safe handling.
    Shelf Life L-Threonine typically has a shelf life of 2-3 years when stored in a cool, dry place, in tightly sealed containers.
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    More Introduction

    L-Threonine from a Manufacturer’s Perspective: What It Means For Users

    Understanding L-Threonine and Its Real-World Role

    L-Threonine takes a prominent place in amino acid production because it does more than just fill a spot on a feed label. Here, on the front lines of fermentation, drying, and packaging, we see every possible challenge tied to its sourcing, production, and use. Rather than offering promises from a polished brochure, it helps to share honest ground-level details. L-Threonine is an essential amino acid. In the feed additive business, “essential” isn’t a marketing term — it means animals can’t produce threonine on their own and look to their diet. Swine and poultry diets run richer and more efficiently on formulas balanced with pure L-Threonine, letting nutritionists adjust crude protein downward while keeping growth and health on track. For nearly two decades, our lines have produced standard and pure crystalline L-Threonine, including top-selling grades like 98.5% minimum purity.

    Starting with Source: Why Feed Grade Means Something

    Raw materials make or break each batch. Our L-Threonine runs start from fine-tuned microbial fermentation, using thoroughly screened genetically optimized bacterial strains. We choose substrate inputs with proven records for non-GMO traceability, absence of animal byproducts, and clean, reproducible yield. This discipline means the final powder contains nothing left over from the fermentation that hasn’t been purposely recovered or removed. Consistent production not only satisfies auditors, but our own mixing teams notice when a batch fails to dry right or smells off — this is a hands-on field. After separation, filtration, and crystallization, the product flows directly to drying and blending, where each step is monitored for dust and moisture content. With every run, we produce a white to off-white crystalline powder: bulk density around 0.5-0.7 g/cm³, and moisture kept low to avoid caking or clumps in feed silos. We pack threonine into multi-layer paper bags with polyethylene liners. This might seem a small thing, but every feed mill operator knows that one moisture leak can ruin a month’s inventory or turn a supply room into a mold trap.

    Specification Isn’t Just Numbers – It’s Day-To-Day Usability

    Every experienced feed formulator knows that published specifications don’t always tell the full story. Yes, you’ll see a typical purity of ≥98.5% (dry basis) on our analysis sheets, with residue and heavy metal tests below tough international standards. Those details count. We submit our products to both third-party and in-house QC — not because a certificate says so, but because a low-level contaminant or wrongly quantified active amino acid can disrupt an entire industry’s trust. We also measure for loss on drying, chloride, sulfates, and conduct tests for color and flow. A specification is only as good as the consistency behind it, and here, repeatable results — especially over years — are our yardstick.

    How L-Threonine Makes a Difference in Animal Nutrition

    From a manufacturer’s perspective, the impact of L-Threonine is seen right where feed comes off the mixer. Nutritionists balancing protein and amino acids are not after fancy words; they want efficiency and measurable outcomes. Including synthetic threonine allows producers to reduce soybean meal or fish meal content. Nitrogen burden drops in manure, which can mean lower costs for waste management and a smaller environmental footprint. Feed costs don’t just hinge on ingredient prices, but how well each additive translates into better conversion rates — heavier broilers per kilogram of feed, stronger piglets, and in some markets, improved egg yields. One large integrator running their own formulation labs tracked improvements in average daily gain over twelve consecutive cycles when switching to direct L-Threonine supplementation. This isn’t magic, but predictable protein optimization.

    Comparing to Other Amino Acids: Why L-Threonine Has a Unique Place

    In the amino acid world, threonine often gets compared to lysine, methionine, and tryptophan. Each has its own story, but the difference isn’t just about numbers or current market prices. If a diet lacks enough threonine — no matter how much lysine it contains — growth stalls. Lysine stands as the “first limiting” amino acid in most swine feeds, but threonine rises quickly to the second or third spot, especially as feed formulations aim to cut crude protein yet keep performance. Methionine, crucial to poultry, pairs with threonine during times of stress or high productivity. Threonine particularly supports gut barrier integrity and mucin production, beyond just muscle accretion. When we collaborate with our feed partners, questions about cost-effectiveness, bioavailability, and dusting losses come up. L-Threonine, as a free-form, crystalline powder, blends into premix or direct addition. Where coated or encapsulated forms are sometimes necessary for special conditions, pure crystalline threonine continues to dominate because of its efficiency and shelf stability.

    L-Threonine vs. Protein Ingredients: The Value Proposition

    Switching out soybean meal or fish meal for amino acid supplementation still provokes pushback in some markets. Years ago, nutritionists swore by high-protein base diets because of tradition and ease of supply chain. As environmental regulations tightened and raw material prices fluctuated, feed mills realized a kilogram of pure threonine could offset several kilograms of natural protein. Ammonia and nitrogen excretion drops measurably, which means compliance gets easier and barns run fresher. Some critics argued that synthetic amino acids “are all the same,” questioning absorption or utilization. Trials conducted inside our own customer network indicated no negative impacts at recommended inclusion rates, and in some trials, results matched or outperformed full high-protein meals. Our approach has always been to encourage risk-averse customers to trial the product, monitor feed conversion, and compare manure output. Performance and results, not promises, guide adoption. Consistency in mixing, dust control, and proper measurement tools at the mill level often decide the success of a new additive.

    Feed Mixer Compatibility and Plant Handling Practicalities

    Feed mills work fast, and anything that slows down batching, fouls up mixing times, or causes dust risk earns a chilly reception. We focus on granulation and the absence of fines — not only for worker safety but to make sure every dose goes into the feed and not out the exhaust fan. Our L-Threonine offers stable free-flowing characteristics, and tightly controlled particle sizes minimize separation in transit. We spent years sorting out dryer configurations and cooling methods to cut caking issues, which saves headaches for shift managers running through dozens of rounds per day. We guarantee batch traceability down to daily fermentation runs, so any issue can be traced by date code, should a customer need a complete record for recall or troubleshooting.

    Ensuring Safety and Positive Results Through Every Shipment

    Adding to feed brings questions about safety, both for livestock and handlers. Our operators conduct daily airborne dust monitoring and personal sampling routines, not just to tick a box for audits, but to avoid chronic respiratory complaints in people packing and handling raw powder. We’ve reduced dusting through ventilation improvements and tweaks in bagging protocols. End users sometimes fret about possible off-odors, cross-contamination, or trace antibiotics. Our plant runs multiple rinsing and full-system purges between product lines. The microbial strains used for fermentation have food safety approvals, and every outgoing batch passes through multi-point screening before loading. Customer feedback prompted us to reinforce tamper-evident bag closures and switch to more durable packaging liners, lowering the complaints tied to breakage in storage or shipment.

    International Logistics: Keeping L-Threonine Stable and Reliable

    Exporting to more than 20 countries exposes weaknesses quickly. We’ve learned the cost of underestimating moisture ingress in long ocean voyages. Collaborating with logistics operators taught us the signs of fumigation agent residues, and we reformulated packaging layers to pass stringent destination tests. Our warehouse sits adjacent to final packaging, reducing lags between final QC inspection and export loading. Most buyers in tropical climates ask about shelf life and quality under fluctuating humidity. We’ve run six-month controlled storage trials and adjust product lot cycles to shorten potential time-in-storage, especially in markets with erratic customs delays.

    Sustainability Pressures and Fermentation Technology

    Feed ingredient buyers are under more pressure to consider environmental impact in every purchase. We track sustainability in our production: water usage, energy per kiloton, and waste valorization all count. We invested in joint research projects on lowering power requirements from upstream fermenters and streamlined microbial recycling. Not every customer calculates the carbon equivalent footprint, but those questions come more often than ever before. Byproduct streams move to on-site energy recovery plants or are converted to fertilizer ingredients, rather than discharged. In some years, we adjusted fermentation media to include more locally sourced raw material as import costs or availability shifted with trade regulations.

    Quality Assurance Beyond the Lab – Practical Lessons in Risk Management

    Quality isn’t only about composition statistics or certified certificates. Incidents with contaminants or storage failures can undo months of credibility. To navigate this, we built a direct feedback channel between our QC lab, production, and distribution groups. If a bag tests out-of-spec on moisture or color, it never leaves the dock. Recent years brought more on-site audits by end users and regulators, and more demand for transparency in batch sampling. Our teams invite customer technicians to witness blending and sampling as part of regular plant tours, reinforcing the link between our process and real feed performance.

    Differences from Competing Products: Transparency and Traceability in Practice

    Where some other L-Threonine brands enter the market through multiple intermediaries, our direct-to-end-user commitment shortens the communication loop. In samples run blind by several major feed manufacturers, our product showed lower dusting losses and more consistent blending characteristics at high mixer speeds. We avoided synthetic colorants or masking agents and kept to simple, reproducible ingredient lists. In the rare event of a complaint or return, our shipping logs tie back to the exact fermentation run, so answering technical questions means drawing on firsthand plant and lab records — not just chasing a distributor for missing data.

    Handling Customer Feedback and Field Results

    No lab result trumps field performance in broiler barns or swine pens. We maintain technical liaisons with two dozen feed mills, gathering daily practical notes — not just statistical measures, but insights from people adjusting mixers or cleaning bins. Early concerns about threonine’s compatibility with sensitive micronutrient blends prompted new carrier ratios in some customized orders. By focusing on honest trials and practical support, we’ve grown with our customers, not just supplied into their systems. We arrange on-farm usage seminars, track post-feed-off conversions, and invest in answering late-night phone calls from operators puzzled by feed consistency. Our experience tells us that communication and technical reliability mean more over years than fine-tuned price differentials between brands.

    Regulatory Surprises and Market Adaptation

    Raw material origins and traceability regulations continue to shift. Sometimes minor changes in one national code force us to rethink export documentation or test parameters. It’s not unusual to find ourselves matching both the standards of importing and exporting countries, reflecting the complicated world of global commodity movement. We work closely with local inspection bureaus and customs agents. The practical side: adjust batch lotting, run extra third-party assays, and keep an updated dossier on every product leaving the gate.

    What Matters Most to Users: Reliable Results, Flexible Supply, and Honest Communication

    Our customers expect surety in threonine. To keep up, we keep production lines running during high-demand seasons by staggering fermentations around feed market rhythms. Our emergency protocols stack finished inventory in secondary certified storage when storms or power failures threaten. We prioritize lot segregation, so each contract receives a single-source shipment: this shrinks variability and boosts confidence in downstream QC checks. Price wars happen every season, but the users who stay with us return mainly for one reason: continual reliability in their feed outcomes and fair, committed support.

    Looking Ahead: The Next Steps for L-Threonine Manufacturing

    Research into next-generation strains and fermentation efficiencies never stops. We’re partnering with bio-refineries for cleaner inputs and smarter byproduct recycling. Enzyme technology can improve yield, but only if it survives scale-up — a lesson we’ve learned more than once through pilot plant failures. As customers demand more detailed traceability, from original culture to bag, blockchain-based tracking may offer new transparency. This all circles back to fundamentals: get the threonine consistently pure, delivered safely, and matched to customer needs, without complicating the process so much that feed plants struggle or farmers mistrust the product.

    Summary: L-Threonine in the Real World

    Years of hands-on work in L-Threonine have shown us what success looks like — and what it takes to get there. The best results come not only from high titers in fermenters or sharp-looking datasheets, but from listening closely to feed millers, nutritionists, and farm managers. Every kilogram that leaves our factory carries with it both our scientific investment and our practical commitment to customers who expect – and deserve – the best for their animals and businesses.