Caffeine

    • Product Name: Caffeine
    • Chemical Name (IUPAC): 1,3,7-Trimethylpurine-2,6-dione
    • CAS No.: 58-08-2
    • Chemical Formula: C8H10N4O2
    • Form/Physical State: Solid
    • Factroy Site: No. 777, Shengli West Road, Yuhui District, Bengbu City, Anhui Province, China
    • Price Inquiry: sales3@ascent-chem.com
    • Manufacturer: Anhui BBCA Group Co., Ltd
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    Specifications

    HS Code

    724340

    Name Caffeine
    Chemical Formula C8H10N4O2
    Molecular Weight 194.19 g/mol
    Appearance white, odorless, crystalline powder
    Solubility In Water 2 g/100 mL (at 25°C)
    Melting Point 235–238°C (455–460°F)
    Cas Number 58-08-2
    Iupac Name 1,3,7-Trimethylpurine-2,6-dione
    Density 1.23 g/cm³
    Boiling Point 178°C at 760 mmHg (sublimes)
    Pka 14.0
    Synonyms guaranine, mateine, theine

    As an accredited Caffeine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Application of Caffeine

    Purity 99%: Caffeine Purity 99% is used in pharmaceutical formulations, where it ensures high efficacy and predictable stimulatory effects.

    Melting Point 238°C: Caffeine Melting Point 238°C is used in energy drink manufacturing, where it maintains product stability during pasteurization.

    Particle Size <50 µm: Caffeine Particle Size <50 µm is used in functional food applications, where it allows rapid dissolution and enhanced bioavailability.

    Stability Temperature 120°C: Caffeine Stability Temperature 120°C is used in instant coffee production, where it withstands thermal processes without degradation.

    Water Solubility 2 g/100 mL: Caffeine Water Solubility 2 g/100 mL is used in beverage concentrates, where it provides uniform dispersion in aqueous solutions.

    Anhydrous Form: Caffeine Anhydrous Form is used in pre-workout supplements, where it delivers consistent potency and faster absorption.

    USP Grade: Caffeine USP Grade is used in over-the-counter medications, where it ensures compliance with regulatory standards and patient safety.

    Optical Purity >99%: Caffeine Optical Purity >99% is used in analytical chemistry studies, where it delivers reliable and reproducible assay results.

    Residual Solvent <10 ppm: Caffeine Residual Solvent <10 ppm is used in sensitive nutraceutical applications, where it minimizes contamination risk and meets quality requirements.

    Microbiological Load <100 CFU/g: Caffeine Microbiological Load <100 CFU/g is used in veterinary formulations, where it ensures microbiological safety and product longevity.

    Packing & Storage
    Packing Caffeine is typically packaged in a sealed, labeled amber glass bottle containing 100 grams, with hazard and handling instructions clearly visible.
    Container Loading (20′ FCL) Container Loading (20′ FCL): Caffeine is typically loaded in 20’ full container loads, securely packaged in drums or bags, totaling around 12-14MT.
    Shipping Caffeine is typically shipped as a dry, white crystalline powder in sealed containers to protect it from moisture and contaminants. It should be transported in compliance with safety regulations, avoiding exposure to heat and direct sunlight. Proper labeling, documentation, and secure packaging are essential to ensure safe and legal shipment.
    Storage Caffeine should be stored in a tightly closed container, protected from light and moisture. It is best kept at room temperature, ideally between 15–25°C (59–77°F), in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers. Ensure the storage area is secure and properly labeled to avoid accidental contamination or misuse of the chemical.
    Shelf Life Caffeine typically has a shelf life of 3-5 years when stored in a cool, dry, airtight container away from light.
    Free Quote

    Competitive Caffeine prices that fit your budget—flexible terms and customized quotes for every order.

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    More Introduction

    Caffeine: How We Make It and Why Purity Sets Ours Apart

    Understanding the Real Caffeine Supply Chain

    Stepping into the world of caffeine production means engaging with chemistry on a daily basis. At our manufacturing plant, caffeine is far more than a simple powder that lands in an energy drink or tablet. It comes from careful synthesis, strict control in sourcing, and years of experience meeting the needs of sectors ranging from pharmaceuticals to food and beverage. Many see caffeine as familiar—something that perks up mornings in cups or hides in the list of ingredients in soft drinks. For producers and scientists, it’s both a substance that needs to deliver performance and a benchmark for manufacturing discipline.

    From Laboratory Bench to Bulk Production

    Every ton of caffeine leaving our facility starts with small batch synthesis and refinement. We have moved from traditional extraction methods—which demand a lot of raw material and leave behind unwanted compounds—to sophisticated chemical routes that guarantee purity and reproducibility. Caffeine, chemically known as 1,3,7-trimethylxanthine, passes through several controlled steps before shipment. We use stringent quality checks at all phases, not just final packaging. This means every shipment is consistent in crystalline form, color, solubility, and purity. Most of the caffeine we produce meets a minimum assay of 99.5% on dry basis, and that's not just a number on a paper. It’s the result of years refining process parameters and equipment cleaning, right down to the filtration and drying steps.

    What Our Caffeine Looks Like and How it Ships

    In our quality control room, we see caffeine as a white to off-white, odorless and slightly bitter-tasting crystalline powder. That’s the standard for bulk production. For pharmaceutical customers, the product has to hit strict levels for heavy metals, residual solvents, and trace organic contaminants. That involves targeted analytics and record-keeping, not just generic batch release. Food and beverage producers want rapid dissolution and no aftertaste. By tweaking drying times and using finer milling equipment, we supply a material that hydrates quickly and blends efficiently, even at high-volume bottling lines.

    Most batches are packed in fiber drums with polyethylene liners, ranging from 25 kg to 50 kg per unit. That’s the scale most manufacturers rely on, and we’ve backed up our cleaning protocols to make sure no cross-contamination occurs. Samples are routinely held for reference—no claims about quality get shrugged off or pushed down the line.

    Caffeine Grades: What Sets Our Product Apart

    We manufacture several grades: food, beverage, pharma, and custom technical. Each serves a unique function. The pharma grade undergoes the most scrutiny. Internal testing screens for every impurity specified by pharmacopeias (USP, EP, JP), along with spectroscopic signatures to confirm there are no rogue chemicals. Beverage grade prioritizes solubility and clarity in solution since any cloudiness in a sports drink can mean customer complaints or product returns. Technical grade skips select steps, which brings cost savings for applications where purity is less critical, such as in some agricultural blends.

    Because we run our own synthesis, rather than just repackaging purified extract, we can tweak production batches to fit these industry demands. That might mean an extra pass through activated carbon filtration or changing a crystallization temperature. We document each batch history, and that trail goes back years for regulatory and repeat customer assurance.

    How We Solve Purity and Safety Challenges

    A major difference between a manufacturer and a trader appears whenever quality issues come up. We've seen caffeine from resellers that contains more than just caffeine—sometimes residual solvents, unreacted precursors, or trace pesticides if botanical extraction was used. Real manufacturing control means holding ourselves to the toughest standard, batch after batch. Every parameter from melting point to pH in solution gets checked against original specifications.

    Customers in the pharmaceutical space ask for full documentation, not just a generic certificate of analysis. Our team responds with complete batch records, chromatograms, and stability data. Beverage formulators come by for technical discussions as they reformulate products, and we welcome them on site—it keeps us honest and tight-knit with industries we serve.

    Chemistry Matters: Production Pathways and Their Impact

    Traditional caffeine comes from extraction out of coffee or tea, but there are drawbacks: inconsistency in raw material lots, agricultural contaminants, and a fluctuating price index. We rely instead on synthetic methods, mainly through the methylation of xanthine derivatives under strictly controlled conditions. This lets us skip the variability of plant harvests, and it narrows the impurity profile to what is manageable at the plant level. Synthetic caffeine is free from pesticide residues that occasionally plague plant-extracted materials. We track every reagent and process water used, making us highly transparent during supplier audits or regulatory inspections.

    There’s a physical difference in the end product, too. Synthetically derived caffeine tends to have a finer, more uniform particle size, with a flow property many customers in tableting or beverage industries prefer. That shows up during blending and filling—our customers have confirmed that the material flows through their dosing hoppers and dissolves much faster than some of the coarser extracted variants.

    Applications That Rely on Caffeine

    Caffeine is a mainstay in pain relief and cold/flu formulations, where it partners with analgesics to improve efficacy and offset drowsiness. Every batch that ships to these customers must prove it meets drug master file requirements and can function reliably in high-speed tablet presses. Energy drinks and sodas rely on fast-dissolving caffeine. Manufacturers hate seeing undissolved particles sticking to the walls of processing tanks; they expect dissolution curves to match precisely with each shipment.

    Researchers and universities use our high-purity caffeine as a reference standard. We also get demand from the cosmetic industry, where exact composition and documented origin play a large role in product formulation for creams and serums.

    Regulatory Compliance and Auditable Supply

    Markets like North America, Europe, and Japan have set the bar high for ingredient traceability. We respond by logging every raw material lot, ensuring chain of custody, and maintaining segregated storage for finished and in-process material. Food safety certifications, FDA and EU regulations, and even Kosher/Halal certifications are checked by internal and third-party teams each year. Caffeine is often regulated as both a food additive and a pharmaceutical active, so strict cross-sector controls matter. Our audits include actual line-by-line exposure of documents and physical plant walkthroughs, not just paperwork.

    Buyers expect more than a signed sheet—they want to see testing logs, cleaning protocols after every batch, pest control for warehouse areas, and logs of every plant visitor. By producing caffeine in a dedicated facility, we take on these challenges rather than leaving risk to a distant supplier. This approach is a direct result of lessons learned over decades, often after seeing loopholes in “one size fits all” supply chains from trading houses.

    Why Caffeine Quality Isn’t “One Product Fits All”

    Many assume all caffeine is interchangeable. Years in manufacturing say otherwise. Each downstream customer applies it differently—solid dose drugs, clear beverages, powder premixes. High flowability means less bridging in feeding systems. Narrow particle size distribution helps during blending and prevents caking during storage. Lower impurity levels reduce off-tastes in flavored drinks and cut down negative interactions in pharma combinations.

    Outside the large customers, we see interest from specialty sectors—animal health, sports nutrition, analytical standards—where requests for tweaks in form (granular, micronized), documentation, or even packaging impact the production cycle. Our plant doesn’t look at these demands as headaches; they’re a sign the market keeps evolving. It keeps our process engineers and technical staff engaged—trialing new production approaches, improving bulk handling equipment, or optimizing post-drying parameters for end-user needs.

    Caffeine Compared to Other Stimulants and Ingredients

    Many functional products look at alternatives like guarana, green tea extract, or synthetic compounds such as theacrine. Unlike complex botanical extracts, synthetic caffeine comes standard with a consistent one-ingredient profile, making it easier for downstream manufacturers to maintain label transparency and avoid regulatory tangles. In tablet or capsule form, batch-to-batch consistency means formulators don’t have to revalidate every time a new shipment arrives. That reliability translates directly into cost savings at the QA/QC level.

    Guarana, for example, contains natural caffeine but also other xanthines and polyphenols. The flavor profile is harder to mask in soft drinks. Tea extracts bring along catechins and sometimes heavy metals, depending on source and lot. Synthetically made caffeine keeps these risks off the table. Looking beyond regulatory and production simplicity, synthetic caffeine provides the certainty food technologists and pharmacists demand when developing new formulations.

    The Importance of Reliable Supply and Traceability

    Supply chain disruptions—crop failures, port closures, regulatory embargoes—put strain on natural caffeine supplies. Manufacturing our own, we sidestep sudden price surges tied to poor harvests in coffee or tea growing regions. We control timing, batch sizes, and production frequency, ensuring customers are not left waiting or scrambling to change formulas on short notice.

    Traceability plays a large role in maintaining trust with buyers worldwide. Every shipment leaving our dock includes not only a lot number but a full production dossier. If a batch ever gets flagged or questioned, we go back through our facility database and immediately retrieve full production, testing, and storage history. That's not a luxury given today’s global safety recalls; it’s a necessity.

    On the Ground: How We Manage Inventory and Logistics

    Transporting caffeine requires understanding chemical compatibility during shipping and storage. Packed in sealed drums or bags, the material stays dry and stable, as moisture pickup leads to caking and difficulties in downstream processing. Warehouses keep humidity and temperature in check—not only for product integrity but to comply with food and pharma storage guidelines.

    Our logistics teams schedule shipments both domestically and internationally, keeping a close eye on regulatory approvals for every destination. Customs officials in some countries have specific labeling or documentation rules. We work closely with regulatory consultants to keep shipments moving. Logistics headaches rarely come from inside the walls of our plant; most issues arise from the shifting sands of port and border policies. Having all batch records and safety documents in digital form means less scrambling during customs questions and more rapid response when customers need support.

    Why We Invest in Analytical Methods and Human Expertise

    Caffeine purity depends not just on equipment, but on trained analysts who understand chromatograms, know how to spot trends during process runs, and pay attention to small details—a yellowish tint, a slight off-odor. Our laboratories run HPLC, UV, and titration methods to confirm each batch against internal standards and regulatory monographs.

    We train staff continuously, not because auditors say so, but because market demands shift fast. As novel beverage formats arrive on the shelves or as regulatory limits tighten for unspecified impurities, we invest in both people and analytical technology. This approach brings a level of transparency and confidence both for our internal team and for customers placing large, recurring orders. We share our non-confidential analytical approach during plant visits or technical audits, believing that an open book is the best way to show reliability in a crowded market.

    Industry Trends: What’s Changing and How We Respond

    Demand for caffeine keeps evolving. Over the past decade, sports nutrition and functional food categories have risen sharply, bringing new formulation and labeling challenges. Sugar free and zero-calorie beverages often need smaller particle sizes to dissolve quickly and avoid settling. Some pharmaceutical applications seek micronized variants for rapid absorption in flash-dissolving tablets—a trend we met by investing in jet milling and enhanced drying systems.

    Sustainability claims increasingly matter in finished products. We see questions about environmental impact, energy use in synthesis and drying, and waste management. Years ago, our industry would have dismissed these issues; now we treat them seriously, benchmarking our water recycling programs, energy consumption per kilogram of output, and solvent recovery. We discuss sustainability openly on request, recognizing it’s not just a buzzword but an operational necessity for long-term growth.

    Challenges for Caffeine Manufacturers and how We Tackle Them

    Caffeine supply doesn’t run without challenges. Scaling up production needs detailed process control to avoid runaway impurities or yields falling below targets. Any operational issue—reactor fouling, filter blockages, unwanted side-reactions—can quickly force delays or lost batches. Every setback sharpens our process; it’s how we developed an internal system for flagging deviations and tracing them back for root-cause analysis.

    External issues also loom large: global transport fluctuations, rising raw material costs, ever-tightening residue limits. We face these by keeping stock buffers, running forecast models, and contracting forward raw material inventories where possible. Every team member is encouraged to spot problems and propose ways to improve, whether it’s tweaking a pump schedule or piloting new drying equipment.

    We keep a regular feedback loop with end users, often through technical workshops and on-site visits. Many of our best process tweaks started with small field complaints—dust levels in a blender, minor color shifts in reprocessed batches, changes in taste panel results. Good manufacturing comes from building on these observations, never just assuming a process runs well because it ran well yesterday.

    What Customers Should Ask from Their Caffeine Supplier

    Too often, we see buyers selecting caffeine on price alone. That choice opens the door to variable quality, instability in supply, or missing documentation, especially from brokers or companies without manufacturing roots. We recommend asking about batch-to-batch consistency, documented impurity levels, traceability, and flexibility in meeting special application demands. Building a real partnership with a manufacturer brings more transparent communication and the ability to adapt formulations or packaging to evolving industry requirements.

    Customers who require on-time performance, regulatory compliance, and technical support benefit from direct engagement with a manufacturer. We run open books for audits, ship samples for joint testing, and respond promptly to queries—because downtime and off-spec batches cost everyone across the chain.

    Looking Forward: Committing to Quality and Transparency

    As caffeine applications become more sophisticated and regulations grow tighter, only those manufacturers who invest in traceable, documented, and customizable processes will lead the industry. We believe that every shipment carries our reputation, one batch at a time, backed by years of improvement and a supply team that knows the stakes. That’s how we continue to build lasting relationships, not just transactions.

    In the field of caffeine production, being an active manufacturer brings both challenge and pride. It means seeing caffeine not as a generic product, but as a critical ingredient that supports medical advances, consumer favorites, and industrial innovation. Reliability, documentation, and a willingness to keep evolving—these set us apart in a market that too often settles for the bare minimum. We encourage our partners and peers to expect more, ask hard questions, and work with those who are ready to answer with real, grounded experience.