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HS Code |
132946 |
| Chemical Name | L-Valine |
| Molecular Formula | C5H11NO2 |
| Molar Mass | 117.15 g/mol |
| Cas Number | 72-18-4 |
| Appearance | White crystalline powder |
| Solubility In Water | 8.8 g/L (20°C) |
| Melting Point | 298 °C (decomposes) |
| Isoelectric Point | 5.96 |
| Density | 1.23 g/cm³ |
| Optical Rotation | [α]D20 +26.6° (c=8 in 6N HCl) |
| Storage Conditions | Store at room temperature, dry and tightly closed |
| Biological Role | Essential amino acid |
| Synonyms | Val; 2-Amino-3-methylbutanoic acid |
As an accredited L-Valine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
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Purity 99%: L-Valine Purity 99% is used in pharmaceutical formulations, where it ensures high bioavailability and consistent therapeutic efficacy. Branch-Chain Amino Acid Content: L-Valine High Branch-Chain Amino Acid Content is used in sports nutrition supplements, where it promotes enhanced muscle protein synthesis and recovery rates. Particle Size 100 mesh: L-Valine Particle Size 100 mesh is used in instant beverage premixes, where it allows for rapid dissolution and homogenous dispersion. Stability Temperature up to 45°C: L-Valine Stability Temperature up to 45°C is used in functional food manufacturing, where it maintains structural integrity during moderate thermal processing. Melting Point 315°C: L-Valine Melting Point 315°C is used in high-temperature extrusion processes, where it provides thermal resistance without degradation. Moisture Content ≤0.5%: L-Valine Moisture Content ≤0.5% is used in lyophilized injection preparations, where it minimizes the risk of microbial growth and improves formulation stability. Optical Rotation -26.2° to -28.8°: L-Valine Optical Rotation -26.2° to -28.8° is used in enantiomer-specific drug synthesis, where it guarantees chiral purity critical for biological activity. Bulk Density 0.55 g/cm³: L-Valine Bulk Density 0.55 g/cm³ is used in solid blend feed additives, where it supports uniform mixing and consistent dosing in animal nutrition. Assay ≥98.5% (HPLC): L-Valine Assay ≥98.5% (HPLC) is used in intravenous nutrient solutions, where it ensures precise amino acid composition for clinical applications. Endotoxin Level <0.25 EU/mg: L-Valine Endotoxin Level <0.25 EU/mg is used in biopharmaceutical production, where it ensures endotoxin safety compliant with regulatory standards. |
| Packing | L-Valine is packaged in a 500g white HDPE bottle with a secure screw cap, labeled with product details and safety information. |
| Container Loading (20′ FCL) | 20′ FCL for L-Valine typically loads 15-18 metric tons, packaged in 25kg bags, maximizing space and ensuring secure transport. |
| Shipping | L-Valine is shipped in tightly sealed containers to protect it from moisture and contamination. It is generally transported as a solid powder in fiber drums, polyethylene bags, or other secure packaging. The package is labeled in accordance with safety regulations, and storage during transit is kept in a cool, dry environment away from incompatible substances. |
| Storage | L-Valine should be stored in a tightly sealed container in a cool, dry, and well-ventilated area away from moisture, heat, and incompatible substances. Protect the chemical from direct sunlight and sources of ignition. Keep the storage area clean and clearly labeled. Follow standard laboratory safety protocols and local regulations for safe handling and storage. |
| Shelf Life | L-Valine has a shelf life of 24–36 months when stored in a cool, dry place, tightly sealed, and away from light. |
Competitive L-Valine prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please contact us at +8615365186327 or mail to sales3@ascent-chem.com.
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Tel: +8615365186327
Email: sales3@ascent-chem.com
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L-Valine stands as one of the critical branched-chain amino acids, right alongside leucine and isoleucine. In the years of developing, producing, and fine-tuning L-Valine in our own reactors and fermenters, nothing replaces seeing firsthand how its quality can make or break someone’s process—whether they’re blending feed for livestock, building a premium sports supplement, or formulating medical nutrition. This amino acid isn’t just filling out a label. It’s responsible for muscle growth, tissue repair, nitrogen balance, and more. Each batch we produce must meet that high mark because the end users—from animals on commercial farms to athletes pushing their limits—demand consistent performance every time.
Running L-Valine batches on-site gives us control over not just purity and appearance, but how well it works in the user’s application. Our typical specification runs at a purity of around 98.5% to 99% (on a dry basis), with moisture content kept well in check. Each processing step—fermentation, separation, crystallization, drying—matters. We pay attention to things like particle size, solubility, and even the ease of automatic dosing in larger-scale plants. Customers who use our feed-grade or pharma-grade options tell us that process glitches—like clumping, inconsistent dissolving, or poor flow—haven’t followed our products into their production lines, and that’s deliberate by design.
The physical form we provide—almost always a white or close-to-white crystalline powder—results from years of feedback. Farmers want something that blends directly into compound feed without problems. Formulators in sports or medical nutrition care about both taste and suspension, and we listen. We pay attention to packaging as well. Moisture causes clumping and caking, so packaging lines always run with multi-layer, humidity-resistant bags. You learn what works and what fails after enough years in the factory.
Demand hits us from several directions. In animal feed manufacturing, L-Valine fills gaps in corn- and soybean-based rations that just can’t deliver the right profile of essential amino acids. Producing L-Valine locally lets nutritionists run lower-protein diets while not robbing pigs or poultry of what they need for weight gain, egg laying, or feed efficiency. Most customers running feed mills want steady particle size and a guarantee there’s no scale-forming impurities when mixed with other feed-grade additives. It’s not about theoretical nutrition—it’s delivering performance a truckload at a time, every week, without variability.
In the sports nutrition industry, L-Valine travels a different path. Here, it ends up in formulations with protein powders and BCAA blends focused on muscle repair and stamina. We hear from formulators who follow regulations tightly, reject off-odors or stray flavors, and test for contaminants. They want documentation to prove every batch meets the mark on purity and meets local or global food safety norms. Water solubility plays a large part—if it clumps or doesn’t dissolve easily, it sets off quality complaints in finished products. We run regular solubility checks for this reason, pushing improvements in crystallization and drying time to avoid the hassle of tedious mixing on the user end.
Medical nutrition clients hold us to the strictest standards for color, solubility, and trace contaminant profiles. The L-Valine we supply for medical use stems from select fermentation batches with extra controls in the cleaning and isolation phases. Hospitals and clinics depend on reliability—there’s no room for error in enteral feeds or formulas for surgery recovery. Any minor change in color or taste sets off alarms in these settings, so our QA labs work double duty to lock down consistency batch-to-batch.
OEMs and bulk users reach out with issues ranging from flowability in high-humidity areas to concerns about dioxins or heavy metals common in poorly managed plants. We found early on that source material and fermentation conditions set the baseline for safety and quality—so the team chose raw materials from vetted suppliers, and runs near-constant monitoring for contaminants before anything moves forward in production. This isn’t about ticking GMP checkboxes; it’s about keeping real-world process interruptions from showing up on the customer’s end.
Shipping and storage dynamics taught us more. Early in our operation, some shipments arrived at a customer’s distribution center caked due to high humidity in transit—hard to scoop, impossible to mix, and headed straight for the complaints pile. We added moisture sensors to the packaging line, boosted the drying steps, and reengineered bag liners. Now, even overseas shipments into humid monsoonal areas keep their free-flowing character. It only takes one container’s worth of product loss to realize these changes matter.
In pharmaceutical and medical applications, we chase even more stringent impurity profiles. Unlike animal feed and food, we test for a longer list of potential residues, and batch documentation follows each drum right up to the delivery dock. All trace metal and microbial counts get logged, and the QA team signs off at multiple points, not just final release. We replicate the product’s journey—mixing it in solution, running storage simulations, checking taste and appearance over time. Every observed issue sparks a round of root cause analysis followed by a process change if needed.
Many buyers ask how our amino acid compares to what they’ve sourced from elsewhere. L-Valine might look similar on a certificate of analysis, but anyone blending a ton at a time or preparing a small-batch high-end supplement can spot real-world differences. It often comes down to how much time is sunk mixing difficult lots or dealing with fines creating dust. We grind and sieve to hit a target particle size range known to reduce airborne powder and speed up blending. In large feed mills, this means less time cleaning up and more time focusing on quality control.
Comparisons with leucine and isoleucine surface regularly. L-Valine works differently in animals used as monogastric livestock, patching up gaps in feeds heavy on cereal grains. Its lower solubility in water compared with some other amino acids shapes how it behaves in drinks and supplements. Customers see less solution haze compared to leucine, but also expect tailored mixing techniques in beverages. We support them with data and hands-on advice collected over years of plant trials.
In high-stakes uses, including injectable nutrition or infant formulations, purity and trace impurity levels matter as much as concentration. We reserve special lots for these purposes, running extended filtration and washing steps to keep residual solvents or endotoxins below detection. It would be easy to claim every product fits every use, but experience teaches the opposite: every application brings different hurdles, and we build our line-up to match these specific needs on the ground.
Sourcing raw materials for fermentation led to periodic disruptions. Corn prices rise and fall, sugar markets get tight, and quality from some suppliers fluctuates batch to batch. We started dual-sourcing, keeping a list of second and third-tier backups, and investing in long-term relationships with suppliers passing strict audits. Our technical team routinely pressures suppliers for analysis certificates and random spot checks. These actions build backup capacity, so customer supply never suffers if a primary source stumbles.
Energy consumption and production emissions concern many larger buyers, especially in regions with carbon taxes or sustainability frameworks. We invested in heat recovery from fermenters, greenhouse gas monitoring, and waste management systems. Our plant slashes water and energy use per ton compared to conventional processes. Customers requiring environmental reporting receive regular updates, not just a snapshot or standalone certification. We keep detailed life cycle assessments on file, able to share numbers when required for regulatory checks or eco-label applications.
L-Valine suffers from counterfeiting issues—a reality in global trade. Some “products” offered on generic e-commerce platforms or through shadow traders show poor purity or adulteration, risking feed and food sector safety. Over the years, we implemented track-and-trace coding on every pallet, locked down supply chains, and steered buyers toward direct purchase. Users sending samples for independent testing find our batches actually deliver what the paperwork claims. It’s not flashy, but it prevents a world of problems in finished goods.
Progress rarely follows a straight line. Field complaints and unsolicited bits of advice from end users shape not just our product specs, but how we run the manufacturing floor. One customer’s rapid-sedimenting batch of L-Valine in a high-protein beverage led us to alter the drying and sieving sequence, tightening the cutoff at the fine end of the spectrum. Years later, the issue never reappeared, and that customer’s trust fueled a multi-year supply agreement.
Feed mills flagged increased dusting at transfer points. After changing the crystallization temperature and tweaking post-cooling conveyor speeds, product handling improved across dozens of factories. The same hands-on approach guides our adjustments to microbial control or heavy metal risks when new sources of water or process aids come into the plant. Our experience shows that attention to seemingly minor feedback prevents major supply interruptions on a wide scale.
Questions about shelf life show up every quarter. We used to check only sealed pack stability. Now accelerated aging studies span six and twelve months under different humidity and temperature profiles. We track color and odor changes, moisture drift, caking, and solubility shifts. The end result is a real-world guarantee—not theoretical, but rooted in experience drawn from keeping production lines running through heat waves, cold snaps, and shipping delays.
Valine, leucine, and isoleucine head the branched-chain amino acid category, but each pulls different weight in practical use. Valine fills out synthetic blends where the natural ration composition falls short—corn and soybean meal diets benefit most, as they typically restrict valine. Leucine evokes extra muscle-building attention in supplements, but Valine features more prominently in finishing pig and poultry rations, where cost and precise amino-acid balances drive the best returns. Many supplement makers prefer our pure L-Valine over combined BCAA mixes so they can control the ratio and avoid taste conflicts.
Compared to non-branched amino acids—such as lysine or methionine—L-Valine usually adds late in formulation, targeting fine adjustments for performance rather than basic structure. Incomplete or overly generic blends risk imbalance, causing waste or feed inefficiency. We field questions about replacing one amino acid with another, and always point back to the science and our own plant experiments. Data and customer outcomes trump sales talk—if Valine isn’t needed, we say so, knowing it builds confidence for the next purchase.
Our own analytic and application labs compare trace impurity loads—chloride, sulfate, ash, and trace metals—batch by batch, so there’s never a surprise in the final product. L-Valine’s lower reactivity with certain premix ingredients and flavors makes it preferred for sensitive formulations in both food and medical applications. Sports and infant nutrition developers flag off-notes and solubility as sticking points with lower-grade material, but those issues don’t track back to our production line anymore due to repeated optimization.
Export markets add a layer of complexity many outside the factory might not see. Feed additives carry different allowed residue levels by region; dietary supplement grades undergo customs testing for particular contaminants. We coordinate with labs on multiple continents, keeping paperwork tight to avoid shipment holds at border points. Our technical team participates in each round of regulatory updates and adapts the SOPs for production and QA accordingly.
Auditors and regulators show up unannounced or on short notice. Their testing focuses on dioxins, heavy metals, antibiotic residues, and genetically modified material status. We collect samples, run traceability reports, and walk through the process with inspectors in real time—as much a matter of confidence as compliance. We keep route maps of every lot’s journey from fermentation tank to final bag, knowing real-world traceability cuts through both suspicion and delay.
Ongoing research into alternative fermentation feedstocks and improved microbial strains points toward efficiency jumps in the coming years. Our plant’s R&D wing collaborates with academic labs and equipment makers, taking pilot-scale tests up to factory-level application with a focus on sustainability and process reliability. We expect production costs and emissions to decline even further, translating into a better deal and lower footprint for downstream users.
Researchers uncover new uses for L-Valine in therapeutic nutrition, especially in cases ranging from chronic renal failure to metabolic disorders. Direct feedback from clinics and research organizations drives us to refine QA protocols, keep purity at the highest possible levels, and anticipate the documentation needs for new regulatory spaces. Each new finding or feedback loop leads to small but important tweaks across raw material selection, fermentation parameters, product testing, and packaging controls.
Manufacturing L-Valine at scale involves years of trial, process troubleshooting, and solution-building. Every improvement builds off the last complaint, feedback note, or market trend spotted by people working with the product every day. The lessons learned show up as fewer delays, less waste, higher downstream efficiency, and consistent satisfaction—with no shortcuts or unproven claims. Readers interested in using L-Valine—whether in feed milling, supplements, or medical formulations—can talk directly to people who have followed the product from fermentation to finished package, not just sales teams reading from a specification sheet.
For anyone considering L-Valine, the story doesn’t end with a percentage of purity or a single batch’s performance. The bigger picture covers dependable sourcing, repeatable quality, straightforward blending, supply security, and ongoing support that responds to changing field conditions. Feedback loops, constant process review, and long-term plant investment combine to give real users the best possible outcome—every shipment, every order, every batch. Years of experience at every step leave us with one certainty: real quality covers not just analysis reports, but the entire journey from raw material to successful application.