Ofloxacin Tablet

    • Product Name: Ofloxacin Tablet
    • Chemical Name (IUPAC): (RS)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
    • CAS No.: 82419-36-1
    • Chemical Formula: C18H20FN3O4
    • Form/Physical State: Tablet
    • Factroy Site: No. 777, Shengli West Road, Yuhui District, Bengbu City, Anhui Province, China
    • Price Inquiry: sales3@ascent-chem.com
    • Manufacturer: Anhui BBCA Group Co., Ltd
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    Specifications

    HS Code

    351318

    Name Ofloxacin Tablet
    Active Ingredient Ofloxacin
    Drug Class Fluoroquinolone antibiotic
    Strength 200 mg, 400 mg (varies by manufacturer)
    Route Of Administration Oral
    Common Indications Bacterial infections, urinary tract infections, respiratory tract infections, skin infections
    Dosage Form Tablet
    Prescription Status Prescription only
    Storage Conditions Store below 25°C in a dry place
    Side Effects Nausea, diarrhea, headache, dizziness, insomnia
    Pregnancy Category Category C (use with caution)
    Contraindications Hypersensitivity to ofloxacin or other quinolones
    Manufacturer Various

    As an accredited Ofloxacin Tablet factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Application of Ofloxacin Tablet

    Dosage Strength: Ofloxacin Tablet 200 mg is used in the treatment of urinary tract infections, where it ensures rapid bacterial clearance and symptom relief.

    Purity: Ofloxacin Tablet with 99.5% API purity is used in management of respiratory tract infections, where it results in consistent therapeutic efficacy.

    Dissolution Rate: Ofloxacin Tablet with dissolution rate ≥85% in 30 minutes is used in acute bacterial sinusitis, where it provides prompt onset of action.

    Stability: Ofloxacin Tablet stable at 40°C/75% RH is used in tropical clinical settings, where it maintains potency and shelf life.

    Tablet Hardness: Ofloxacin Tablet with 6 kg/cm² hardness is used for outpatient prescriptions, where it ensures low friability and ease of handling.

    Disintegration Time: Ofloxacin Tablet with disintegration time under 15 minutes is used in emergency infection management, where it delivers fast absorption and clinical response.

    Moisture Content: Ofloxacin Tablet with moisture content <2% is used in long-term storage, where it preserves tablet integrity and chemical stability.

    Impurity Limit: Ofloxacin Tablet containing total impurities below 0.3% is used in pediatric infection treatment, where it reduces risk of adverse effects.

    Particle Size: Ofloxacin Tablet manufactured with API particle size D90 < 20 µm is used for gastrointestinal infections, where it enhances bioavailability and absorption consistency.

    Packaging: Ofloxacin Tablet in blister packaging is used for hospital supply chains, where it prevents contamination and degradation.

    Packing & Storage
    Packing The Ofloxacin Tablet packaging is a white and blue box, containing 10 film-coated tablets, neatly blister-packed and clearly labeled.
    Container Loading (20′ FCL) **Container Loading (20′ FCL):** Ofloxacin Tablets are packed securely, maximizing space, ensuring stability, safety, and compliance with international shipping standards for pharmaceuticals.
    Shipping Ofloxacin Tablets are shipped in tightly sealed, moisture-resistant containers to ensure product stability and safety during transit. Packages are properly labeled according to regulatory requirements and handled with care to prevent damage. Shipments comply with pharmaceutical transport guidelines, maintaining appropriate temperature and safeguarding the tablets from light, contamination, and physical impact.
    Storage Ofloxacin Tablets should be stored at a temperature between 15°C and 30°C (59°F and 86°F), protected from moisture, heat, and direct light. Keep the tablets in their original, tightly closed container. Store away from children and pets. Avoid storing in bathrooms or humid areas to maintain the medication’s stability and effectiveness. Always check the expiration date before use.
    Shelf Life The shelf life of Ofloxacin Tablet is typically 2 to 3 years when stored below 25°C in a dry, cool place.
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    More Introduction

    Introducing Our Ofloxacin Tablets

    Crafting Ofloxacin: Commitment That Runs Deep

    Every pharmacy shelf holds a story. Ours with ofloxacin tablets begins on the manufacturing floor, charting a path that threads together strict discipline, technical rigor, and a responsibility to deliver antibiotics that do the job every time. Many years of hands-on refinement shape the way we produce our ofloxacin tablets. From sourcing pharmaceutical-grade ofloxacin API, batch after batch, we depend on repeatable testing, cleanroom handling, and granular moisture controls—this is routine, not marketing jargon. Each tablet rolling off our line represents split-second decision-making from technicians and chemists with decades on the line.

    Our models offer 200 mg and 400 mg dosage strengths, with round, white, film-coated profiles. We base this on clinical preference—lower doses for children or mild infections, higher doses in line with physician requirements for adults treating more established bacterial threats. No coatings with mystery excipients, and we avoid colorants unless the client’s clinical protocols call for strict tablet differentiation. Tablets are scored where breaking is medically necessary. We don’t chase style points or marketing trends—just practicality, stability, and safe shelf-life.

    The Role of Ofloxacin in Modern Practice

    Ofloxacin represents a class of fluoroquinolones, tackling a spectrum of infections that includes respiratory tract, urinary tract, and soft tissue cases when the stakes mean more than minor discomfort. In real clinics, it’s doctors reaching for a treatment proven to absorb efficiently, respond quickly, and suppress growth of tough bacteria that sidestep penicillins or older sulfamethoxazoles. What our staff hears often: doctors turn to ofloxacin because patient compliance improves with short, direct regimens, and because the risk of side effects, though present like any active antibiotic, proves manageable for most populations.

    Clinics, especially in resource-constrained areas, rely on the dependability of ofloxacin—one of the reasons we adjust our packaging for humid or high-temperature climates, reinforcing seals and cutting air transfer to nearly zero. Our in-house research constantly evaluates which excipients stabilize active ingredient levels best under these conditions. Our practical experience with seasonally variable storage helps us make sure clinics far from distribution centers get the same reliability as a hospital next to our plant.

    Inside the Tablet: What Sets Our Process Apart

    Scaling a batch of ofloxacin starts in a climate-controlled weighing zone. We require every staff member to log calibration stats of balances before measuring the API. After quality chemists check and sign on solvent quality and granulation profile, each blend sits overnight for stabilization before anything compresses under pressure. This gives more consistent weight variation and prevents what pharmacists call “dose flooding” in split tablets—small choices with big impacts down the line.

    Unlike some manufacturers, we never shortchange coating times for speed. The enteric polymers and binders receive stage-by-stage temperature ramping to avoid cracking or uneven dissolution rates—a shortcut here means tablets falling apart before hitting the intestine, and we’ve rejected more than one batch for small cracks only visible under the lamp. Chemical uniformity means little if the user receives half the intended dose due to shoddy film-layering. All these decisions build toward highest reliability even if it means lower throughput; lost batches are absorbed as a cost for quality.

    Finished tablets pass through UV and XRF stations—not for compliance alone, but because fine deviations in tablet weight or unexpected moisture can signal risks way ahead of expiry. Samples taken from every batch get held back for yearlong monitoring, up to triple the regulatory minimums, letting us catch stability issues before outside patients see the product.

    Clinical Use and Patient Experience

    Patients using ofloxacin tablets look for reliability above all. A typical course runs from three to ten days, dictated by infection type. Doctors prefer the fast absorption—patients can expect to achieve effective serum concentrations in as little as an hour. We choose excipients that dissolve well in a range of gut pH levels, since gastric variability affects different age groups. For children or elderly, smaller tablet forms with lower force-to-break values make splitting or swallowing less risky—a practical reality for home care in places without clinical staff.

    Because the tablet’s bitter taste can present patient compliance difficulties, our coatings extend to the edge, completely covering core layers. Direct feedback from outpatient clinics led us to switch formulas a few years back, removing flavoring agents that failed masking tests in real practice. When care homes reported difficulties with tablets sticking to feeding tubes, our formulations team reworked the surface smoothness, landing on a microcrystalline cellulose balance that slides instead of sticks, improving administration for the most fragile patients.

    Our Comparison: Where Ofloxacin Finds Its Role

    Ofloxacin’s standout value lies in the clinical balance between efficacy against gram-negative and gram-positive bacteria and a generally reliable safety record. In our facility, we frequently engage clinicians on where ofloxacin fits compared to other antibiotics (ciprofloxacin, levofloxacin, even far older classes like ampicillin or tetracycline). Ofloxacin persists as the drug of choice for chronic or recurrent urinary tract infections where resistance patterns reduce the reliability of older therapies. Its lower risk of significant liver enzyme increases, compared to more aggressive fluoroquinolones, makes it a preferred agent where bloodwork monitoring isn’t always possible.

    Levofloxacin, chemically a close relative, offers a broader spectrum against atypical respiratory pathogens but often comes at a higher price. Some facilities shy away from it for routine use due to budget, reserving it for cases where resistance data points strongly in its favor. Our ofloxacin tablets provide a cost-effective option still firing on all critical infection targets for which it was originally developed. This helps public health clinics stretch their budgets—and in our business, that translates directly into cycles spent producing for reliability, not just profit.

    Compared to the traditional wide-use broad spectrum agents, ofloxacin tablets produce fewer hypersensitivity reactions, a reality our adverse event surveys confirm year after year. Not all patients react the same, of course, but the practical difference emerges most visibly in rural clinics that track recoveries and relapses among larger populations over time.

    What the Manufacturing Floor Teaches Us

    Years on the manufacturing floor teach that clean systems, batch-to-batch consistency, and unbroken cold chain storage ultimately matter more than promises on a label. Efforts go beyond regulatory minimums—our company deploys continuous training, real-time environmental monitoring, and monthly external audits. We wake up to the reality that small lapses in humidity control or overlooked wear in a granulator blade can spiral into far-reaching product impacts. Most customers never see this side, but behind each tablet’s tidy blister pack, our logs tell stories of caught errors, immediate stoppages, and hard lessons learned in real-time.

    Because our ofloxacin tablets end up in both city hospitals and remote clinics, every part of the supply line must function with the assumption that no rescue batch arrives in time. This has led us to build redundancies in API sourcing—one factory in Europe, the other in Asia—maintaining identical documentation and QC standards. For moisture and oxygen exposure, our film choices stem directly from studying distribution failures: we’ve replaced packaging types twice over in response to weather-based losses in tropical regions, drawing from firsthand field reports.

    Feedback Driving Practical Change

    Our product improvement cycles flow straight from field data. Regular contact with clinicians, pharmacists, and even logistics managers provides insight rarely generated in focus groups. An example: One community hospital observed greater-than-expected fragmentation when pressing tablets from older blister packs. Investigation pointed to a marginal shift in our PVC film supplier—a change we reverted after lab testing validated the field failure. This type of loop, from real end user data through back to the shop floor, steers product development more than any abstract marketing research.

    We continuously track microbial stability using challenge testing, reflecting on how moisture permeation, ambient storage temperature, or unintentional light exposure interact over months in real-world conditions. Solutions often emerge from shared wisdom across our manufacturing team—someone recalling a similar event from a decade prior, with hard evidence logged in a binder, now digitally indexed. Product evolves when lessons are shared and repeated across shifts, across product runs.

    Environmental Responsibility in Manufacturing

    Antibiotic resistance remains an industry-wide challenge. From our perspective as a primary manufacturer, careful stewardship starts with controlling waste streams and discharge points. We process each byproduct through high-temperature incinerators and activated carbon systems, not as a box-ticking exercise, but because repeated, short-term disposals of even low-concentration antibiotic effluent can nudge local resistance patterns. We've instituted routine monitoring at our outflows, inviting third-party verification. These actions stem from realizing our production has downstream human consequences—visible each time a regional antibiogram shifts over years.

    Packaging waste stands as our next frontier. With millions of tablets shipped, the volume of PVC-aluminum waste can’t be ignored. We work with global partners to extend recyclable material use without risking drug stability or storage life. Ongoing pilots target lower-gauge, high-barrier films and streamlined carton box sizing to reduce secondary waste. Feedback from the field, concerning both ease of opening and disposal logistics, shapes the pace of deployment.

    Supply Chain Reliability: Lessons from Disruptions

    Supply shocks—caused by weather events, logistics slowdowns, or sudden surges in demand—have repeatedly tested our risk strategies. Our site experience during past pandemic surges taught us that warehousing reserves for critical antibiotics isn't just a marketing line, but a matter of national preparedness. We leverage dual-site manufacturing and local API reserves to buffer core products, accepting higher storage costs as the price of avoiding shortages that put patient recoveries at risk.

    Real-life stories surface constantly: one year ago, a major logistics freeze in our destination country threatened to break the medicine supply chain for hundreds of clinics. Having both air freight and regional overland partners secured, we shifted shipments overnight, making use of pre-approved quarantine storage until local transport returned. Our relations with local regulatory teams helped expedite customs releases. Supply chain resilience places enormous weight on good planning, but flexibility and human coordination drive actual results day to day.

    Training and Quality—What It Means for Your Medicine

    Tablets only prove their worth when each one matches the approved spec. Our in-house labs run dissolution, weight variation, content uniformity, and microbial limit tests batch by batch. Our protocols go further than minimums—adopting additional randomization and post-marketing sampling. Staff rotate through cross-training every quarter; our system works not because a few experts drive the shop floor, but because knowledge gets spread and refreshed at each level.

    The clearest metric from our years manufacturing ofloxacin tablets: complaint rates have fallen steadily as monitoring systems improve and reporting becomes less bureaucratic. Early warning built on near-real-time data means we trace issues at the lot level within hours, addressing them before complaints reach regulatory authorities or patients. This culture of rapid response comes from continuous feedback and professional pride in work done right.

    Looking Forward: How We Keep Earning Trust

    Public confidence in antibiotics erodes with every news story about poor-quality generics, or resistance linked to excessive or careless use. We know our role carries more than commercial weight—it connects directly to health, life, and public trust. To keep this trust, we invest in staff education, equipment renewal, and technology upgrades that don’t always show as improved margins but do result in fewer defects, greater repeat order rates, and longer-term partnerships with big hospitals and community clinics alike.

    We embed patient safety and end-user voice into every production and optimization cycle, backed with transparent reporting. Pharmaceutical inspections are not interruptions; they are welcomed, collaborative audits that help us refine our practices further. Our teams walk every step of the process, from API synthesis to tableting, coat application, and final packaging. These investments pay the highest dividend: returning customers, low batch rejection rates, and a daily workflow anchored in expertise, not shortcuts.

    The Human Factor: Why We Choose Steady Over Flashy

    Our position at the production level gives us a responsibility to the end patient—outcomes aren’t theoretical. By maintaining close ties with field practitioners and revisiting real stories from wards, we better anticipate what’s at stake every time a tablet is dispensed. We avoid short-term cost savings at the expense of performance, refusing to race toward more decorative packaging or marginal shifts in excipient blend that risk changing patient experience.

    The business of antibiotics doesn’t reward flashy launches or trendy add-ons. Instead, we treat reliability and safety as watchwords, trusting that steady progress—recorded in painstaking logs and ongoing staff training—delivers more good than chasing daily headlines. Every patient, prescriber, and pharmacist using ofloxacin deserves the quiet confidence that comes from a well-made product, built on solid ground.